Resolving the issue of those using MSN Messenger (Error Code: 80072745)

A lot of people are experiencing problems with MSN Messenger, especially the latest version. MSN Messenger 8, also known as Messenger Live!
I expeirienced this problem myself, relating to Error Code: 80072745. It was a pain in the ass, it became rather annoying that I could not sign in.
I kept getting the following message “We were unable to sign you in to the MSN Messenger, possibly because of a problem with your Internet connection. Please try again later. 80072745″
I began to try signing in to an online messenger service, such as http://webmessenger.msn.com, I was able to sign in fine, so blaming the server was out of the question.
If you are experiencing this problem, I sugest you try the following steps.

In my personal case the problem was is Eset NOD32 Antivirus, and I simply removed MSN from it's Web access protection list.

(Before you do the following steps, be sure that your Anti-Virus is fully updated, and you have run a full system scan for viruses/trojans.)
1: If you are using a Firewall, be sure that MSN Messenger has been granted access.
2: Clear your Internet Explorer’s Cache and Cookies. — Open Internet Explorer, click on Tools>Options. Delete Files and Delete Cookies. (If you are using something different, Mozilla Firefox, they can be found in the Privacy TAB).
3: MSN Messenger is required for “Use SSL 2.0″ and “Use SSL 3.0″ are enabled. — Open Internet Explorer, click on Tools>Options. Go to Advanced, scroll down and check them both.
4: Final step, Go to Start>Run and type in cmd and press enter. Then enter the commands below one by one, and then press enter for each command:regsvr32 softpub.dll( A message will appear, click ok. Then type in the next command, and repeat)regsvr32 wintrust.dllregsvr32 initpki.dllregsvr32 MSXML3.dll
After doing this, restart your Modem/Router, then try to sign in. If you are still unable to sign in, restart your computer.
Sometimes spyware/addware can be the problem, I recommend that you use Spybot - Search and Destroy. Click here for the Spybot website.
If you need any more information, feel free to contact me. martin@martinjknight.com
Please note that this information was taken from a well known source and was not created by me.
Here is another way of possibly resolving the problem, which was posted by internet-kaltersia. You may want to try this out if the previous information didn’t work.
Here is the crazy thing I had to do to fix this…
Quote from Raphael
Dear all if you have not heard simply add these addresses to the following file that should be opened with notepad and MSN will work.
C:\WINDOWS\system32\drivers\etc\hosts - (When you open the ETC folder open the HOSTS file using notepad).
insert the following addresses:65.54.239.80 messenger.hotmail.com65.54.239.80 dp.msnmessenger.skadns.net
(INSERT THEM DIRECTLY UNDER THE OTHER 2 ADDRESSES AND ALIGN THEM WITH TAB.)
Easy done … good luck.
Thank you for that additional information!

Please note that this information was taken from a well known source and was not created by me.